CPAP in AF Patients With OSA (NCT04513483) | Clinical Trial Compass
CompletedNot Applicable
CPAP in AF Patients With OSA
Taiwan25 participantsStarted 2020-08-07
Plain-language summary
Obstructive sleep apnea is associated with atrial fibrillation. This study is to evaluate the effect of continuous positive airway pressure on the burden of atrial fibrillation in the patients with obstructive sleep apnea and paroxysmal atrial fibrillation.
Who can participate
Age range
18 Years – 80 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion criteria
. men or women aged 18 to 80 years
. paroxysmal AF, diagnosed based on the ACC/AHA/HRS 2014 guideline, and is defined as AF that terminates spontaneously or with intervention within 7 d of onset either by 12-lead EKG, 24-hr Holter, or 14-day ECG monitor.
. OSA, defined as an AHI\>15/hr of sleep, of which \>50% of events are obstructive.
. Informed consent signed
Exclusion criteria
. Moderate-severe valvular heart diseases (regurgitation or stenosis)
. post heart surgery
. Uncontrolled systemic hypertension or pulmonary hypertension
. Use of psychoactive or other drugs that could influence breathing patterns
. Current use of CPAP treatment
. Epworth sleepiness scale\>10
. Congestive heart failure (LVEF≦45%)
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Change of AF burden
Timeframe: 0, 6, 12 months
2
change of left atrium volume
Timeframe: 0, 6, 12 months
3
change of Quality of Life
Timeframe: 0, 6, 12 months
4
Number of participants hospitalized for cardiovascular or all causes