CompletedNot Applicable

A Comparison of Rocuronium 0.3 mg/kg, and 0.9 mg/kg for Induction of Anesthesia in Elderly Patients.

Denmark34 participantsStarted 2020-12-17

Plain-language summary

The number of elderly patients above 80 years is increasing and a large proportion of these patients will require surgery and anesthesia. During anesthesia neuromuscular blocking agents (NMBA) are administered to facilitate intubating conditions and reduce the trauma to the larynx and vocal cords. There is a risk of residual neuromuscular block when using NMBAs like rocuronium. The aim of this study is to determine the onset time, duration of action and effect on intubating conditions after rocuronium 0.3 mg/kg and 0.9 mg/kg in patients with age ≥ 80 years.

Who can participate

Age range80 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Age ≥ 80 * Scheduled to elective surgery (expected duration time of surgery \> 1 hour) under general anesthesia with intubation and use of rocuronium. * American Society of Anesthesiologists (ASA) physical status classification I to III * Informed consent (see appendix 1) * Read and understand Danish Exclusion Criteria: * Neuromuscular disease * Known allergy to rocuronium * Prone position * Indication for rapid sequence induction

What they're measuring

Rocuronium onset time

Timeframe: intraoperative (From start of rocuronium injection to train-of-four (TOF) count of 0)

Trial details

NCT IDNCT04512313

SponsorRigshospitalet, Denmark

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2021-05-18

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