Effect of Chlorhexidine-Induced Oral Care on Ventilator-Related Some Respiratory System Complicat… (NCT04505202) | Clinical Trial Compass
CompletedNot Applicable
Effect of Chlorhexidine-Induced Oral Care on Ventilator-Related Some Respiratory System Complications
Turkey (Türkiye)57 participantsStarted 2019-04-15
Plain-language summary
Ventilator-associated pneumonia and ventilator-associated treakeabronchitis in respiratory tract infections associated with ventilator are common infections in intensive care unit and cause significant morbidity, mortality and health expenditures in nosocomial infections. Adequate and effective oral care by nurses in intensive care patients, possible complications, intensive care unit stay in the intensive care unit and is very important in terms of mortality.
Who can participate
Age range
18 Years – 95 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Age ≥ 18 years
* Admission in critical care with in 24 hours
* Having an endotracheal tube
Exclusion Criteria:
* History of chlorhexidine allergy
* Duration of mechanichal ventilation less than 48 h
* Confirmed diagnosis of pneumonitis before admission in the ICU
* Transfer from another ICU
* Receiving chemotherapy or radiotherapy
* Patients with immunodeficiency
* Patients with tracheostomies
* Required specific oral hygiene procedures
* Facio-maxillary or dental trauma/surgery
* Being pregnant
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Pathogen colonization change
Timeframe: change from baseline pathogen colonization at Day 3
2
Oral assessment guide score change
Timeframe: at the time of admission into the study (day 0), at study day 2 and at day 3
3
Clinical pulmonary infection score change
Timeframe: at the time of admission into the study (day 0), at study day 2 and at day 3
4
rate of tracheobronchitis change
Timeframe: change from baseline the rate of tracheobronchitis at Day 3