UnknownNot Applicable

Fiberoptic Bronchoscopy and Bronchoalveolar Lavage in Critically Ill Ventilated Patients

Belgium15 participantsStarted 2020-09-01

Plain-language summary

Fiberoptic bronchoscopy (FOB) is widely used as a diagnostic or therapeutic procedure in intensive care units. Patients with ARDS or COVID-19 disease often undergoes to these procedures. However, intensive care patients might suffer from serious side effects such as prolonged oxygen desaturation and adverse change in lung compliance and resistance. This study aims to evaluate these changes and determine their impact on patient stability.

Who can participate

Age range

18 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: Mechanically ventilated ICU patients requiring a FOB or FOB + BAL Exclusion Criteria: * PaO2/FiO2 ratio \<100 * Age \< 18 years * Pregnancy * Unstable angina and recent (less than 1 week) myocardial infarction * Uncontrolled cranial hypertension * Major hemodynamic instability * Any previous lung surgery (except for lung transplantation) * Obesity (BMI \> 50) * Chest circumference \> 150 cm * Electronic implanted device (pacemaker, neurostimulator, etc.) Patients who had undergone several bronchoscopy procedures could not be included twice.

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Regional Compliance Variation

Timeframe: From FOB/BAL to 6 hours later

Trial details

NCT IDNCT04502368

SponsorErasme University Hospital

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2021-03-30

Contact for this trial

Francesco Ricottilli, MD

+32(02)5553344 francesco@ricottilli.eu

View on ClinicalTrials.gov More Fiberoptic Bronchoscopy (FOB) trials