UnknownNot Applicable

Isonicotinic Acid Hydrazide (INH) Pretreatment With Misoprostol Versus Misoprostol Alone in Missed Abortion

Egypt240 participantsStarted 2020-09-01

Plain-language summary

The primary endpoint was the success rate of adjuvant isonicotinic acid hydrazide (INH) and misoprostol versus misoprostol alone for medical termination of first-trimester pregnancy.

Who can participate

Age range18 Years – 45 Years

SexFEMALE

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Gestational age less than 70 days gestation (\<10 wks) * Hemoglobin \>10 g/dL. * BMI between 18.5 kg/m2 and 30 kg/m2. * Missed abortion Exclusion Criteria: * Molar pregnancy. * Fibroid uterus. * Uterine anomalies. * Coagulopathy. * Medical disorder that contraindicate induction of abortion (e.g. heart failure). * Previous attempts for induction of abortion in the current pregnancy. * Allergy to misoprostol or letrozole. * Scared uterus (previous myomectomy, cesarean section, hysterectomy and ruptured uterus).

What they're measuring

number of patients with complete abortion

Timeframe: 12 hours

time from induction to abortion

Timeframe: 12 hours

Trial details

NCT IDNCT04500002

SponsorAswan University Hospital

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2021-06-30

Contact for this trial

hany f Sallam, md

+20102435461 hany.farouk@aswu.edu.eg

View on ClinicalTrials.gov More IUCD Complication trials