See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* • Aged \>18 years
* Cirrhotic patients with arterial hypertension
* Endoscopic evidence of medium/large-sized esophageal varices
Exclusion Criteria:
* • History of variceal bleeding or previous primary prevention of varices.
* Portal vein thrombosis or previous porto-systemic shunts as TIPS.
* Patients on drugs affecting portal pressure (beta blockers, nitrates).
* Advanced cardiovascular disease including acute myocardial infarction, atrio-ventricular block, congestive heart failure, chronic peripheral ischemia, severe bradycardia.
* Patients with severe respiratory diseases (COPD, bronchial asthma).
* Uncontrolled diabetes mellitus
* Renal impairment
* Hepatocellular carcinoma
* Allergy to carvedilol
* Pregnancy or lactation