Complex Decongestive Applications in Patients With Lipedema (NCT04492046) | Clinical Trial Compass
CompletedNot Applicable
Complex Decongestive Applications in Patients With Lipedema
Turkey (Türkiye)23 participantsStarted 2019-09-02
Plain-language summary
Lipedema is a rare condition which almost exclusively affects women. The disease is characterized with bilateral, symmetric abnormal accumulation of subcutaneous fat and is often mistaken for simple obesity. In most patients, the hips, buttocks, thighs, knees, and lower legs are affected. Upper extremity involvement has been reported to be present in 80% patients. The hands and feet are never affected. The accumulation of subcutaneous fat and edema results in tenderness, sensitivity to touch and pressure and also pain. Patients also tend to bruise easily even after a minimal trauma. It has been reported that the complaint of pain increases with aging.There is no known cure for lipedema. However, conservative treatment with physiotherapy, manual lymph drainage and compression, also known as complex decongestive physiotherapy is used worldwide as a standard treatment regimen . The aim of this study is to investigate the effect of complex decongestive applications on lower extremity limb circumference and volume in patients with lipedema.
Who can participate
Age range
18 Years – 65 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Being willing to participate in the study
* Being 18-65 years old
* Having a diagnosis of lower extremity lipedema
Exclusion Criteria:
\- Having edematous disease in the lower extremity such as lymphedema or chronic venous insufficiency
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1This trial measured limb volume as its primary outcome in lipedema patients — can you explain what changes in limb volume actually mean for day-to-day symptoms like pain or heaviness, and whether those improvements were meaningful in practice?
2Since this trial is listed as phase 'NA' and focused on complex decongestive therapy rather than a new drug, can you help me understand how the evidence from this kind of study compares to what's already known about standard decongestive treatment for lipedema?
3The trial is now completed — do you know if the results have been published yet, and what they showed about how well complex decongestive applications worked for reducing limb volume in lipedema?
4Given that this study specifically looked at lipedema, which can be misdiagnosed or confused with lymphedema or obesity, how confident are you in my diagnosis, and would the decongestive approaches tested here even be appropriate for my situation?
5Are there standard-of-care decongestive treatments already available to me that are similar to what was studied in this trial, and should I consider those before looking into research-based options?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Limb Volume
Timeframe: Change from Baseline limb volume at 6 weeks