Screening of Gastrointestinal Tract Bleeding Causes Among Chronic Renal Failure Patients (NCT04491669) | Clinical Trial Compass
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Screening of Gastrointestinal Tract Bleeding Causes Among Chronic Renal Failure Patients
100 participantsStarted 2020-10-01
Plain-language summary
The aim of the current study is to screen different causes and characteristics of Gastrointestinal bleeding in Chronic Renal Failure patients at Assuit University Hospital according to their stages based on e GFR (Stage I to IV), in order to assess different modalities of therapeutic intervention from medical therapy up to therapeutic intervention.
Who can participate
SexALL
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Inclusion Criteria:
* One hundred Chronic Renal Failure patients with different stages (stage I to IV) according to the National Kidney Foundation are recruited from inpatients of renal unit in internal medicine department, Assuit university hospitals. Their GFR will assessed by using Chronic Renal Failure EPI equation measured as GFR=166 x(s cr/0.7)-1.209X(0.993)age if female, and GFR=163X(s cr/0.9)-1.209x(0.993)age if male. (Andrews et al 2008).
Chronic Renal Failure staging according to GFR by Chronic Renal Failure EPI is:
* Stage1 in which GFR\>90 mil/min but evidence of kidney damage.
* Stage 2 GFR 60-89 mil/min.
* Stage 3 GFR 30-95 mil/min.
* Stage 4 GFR 15-29 mil/min.
* Stage 5 GFR\<15 mil/min.
Exclusion Criteria:
* All Patients with local causes of Gastrointestinal Bleeding
* Benign and Malignant tumors in Gastrointestinal Tract.
* Patients with Hemorrhoids or anal fissures.
* Patients with Mallory-Weiss tears.
* patients with Diverticular disease.
* patients with Colon polyps.
* patients with infectious causes of GIT bleeding (Salmonella, Shigella)
* patients with Angiodysplasia.
* patients with Esophageal varices
What they're measuring
1
Assessment of different modalities of therapeutic intervention.
Timeframe: one year from October 2020 to October 2021