Active — Not RecruitingNot Applicable

Postoperative Thrombosis Prevention in Patients With CD

China206 participantsStarted 2020-12-01

Plain-language summary

Patients with Cushing disease was randomized to 2 groups. After surgery, the patients were managed with mechanical prevention or mechanical prevention plus anticoagulant drugs(LMWH followed by rivaroxaban), VTE was observed 24h, 5day, 4weeks and 12weeks after surgery.Bleeding events were also recorded.

Who can participate

Age range18 Years – 65 Years

SexALL

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Exclusion criteria

✕. History of VTE before surgery or within 24 hours post-surgery
✕. Acute bacterial endocarditis
✕. Major bleeding events
✕. Thrombocytopenia
✕. Active gastrointestinal ulcers
✕. History of stroke
✕. High risk of bleeding due to clotting abnormalities
✕. Participation in other clinical trials within the last three months

What they're measuring

VTE incidence rate

Timeframe: 12 weeks

Trial details

NCT IDNCT04486859

SponsorHuashan Hospital

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2025-05-01

View on ClinicalTrials.gov More Cushing Disease trials