Performing surgery in utero on fetuses with certain birth defects has led to significant improvements in outcomes after birth; however, many of these infants are born preterm which can decrease the effectiveness of these procedures. The investigators aim to understand the effects of surgery on the maternal and fetal immune system and whether immune activation may be causing some of these infants to be born prematurely.
Age range
18 Years – 50 Years
Sex
FEMALE
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Maternal T cell activation following in utero intervention.
Timeframe: Baseline, 1-2 days post intervention, 1 week post intervention, delivery