UnknownNot Applicable

Incidences, Causes, and Outcomes of Febrile Illness in Rural South and Southeast Asia

Bangladesh, Burma, Cambodia100,000 participantsStarted 2021-08-04

Plain-language summary

The study will collect information to understand the causes and outcomes of febrile illness in rural areas in countries across South and Southeast Asia ( including Cambodia, Laos, Myanmar and Bangladesh). The findings will be used to identify new tests and treatments that can improve the management of febrile patients in the future. This study is funded by the UK Wellcome Trust. The grant reference number is 215604/Z/19/Z

Who can participate

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Documented fever (≥ 37.5°C axillary), hypothermia (\< 35.5°C) and/or history of fever in the last 24 hours. * Willingness and ability to comply with study protocol for the study duration. * Written informed consent given to participate in the trial. Exclusion Criteria: * Currently enrolled in the study * Accident or trauma is the cause for presentation * Presentation ≤ 3 days after routine immunisations

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Local incidence of febrile illness

Timeframe: From Months 0 to 24

Overall incidence of febrile illness

Timeframe: From Months 0 to 24

Mortality

Timeframe: Within approximately 1 month of first presentation to the village health worker or health facility

Morbidity

Timeframe: Over 1 month after first presentation

Trial details

NCT IDNCT04478578

SponsorUniversity of Oxford

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2024-12-01

Contact for this trial

Yoel Lubell, Prof.

+66-857201350 yoel@tropmedres.ac

View on ClinicalTrials.gov More Febrile Illness trials

Plain-language summary

Who can participate

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

What they're measuring

Local incidence of febrile illness

Timeframe: From Months 0 to 24

Overall incidence of febrile illness

Timeframe: From Months 0 to 24

Mortality

Timeframe: Within approximately 1 month of first presentation to the village health worker or health facility

Morbidity

Timeframe: Over 1 month after first presentation