RecruitingNot Applicable

A Prospective Study of a Mosaic Embryo Transfer

United States250 participantsStarted 2020-10-15

Plain-language summary

This research is a prospective study in which the purpose is to investigate the clinical outcomes following the transfer of a mosaic embryo (presence of both chromosomally normal and abnormal cells) that has been screened for preimplantation genetic testing (PGT).

Who can participate

Age range

18 Years – 45 Years

Sex

FEMALE

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Women age 18-45 Infertile women who have completed an IVF cycle with PGT at the Colorado Center for Reproductive Medicine (CCRM) that have a mosaic embryo * Patients can be of any race, culture, sexual orientation or ethnicity * Patients that are willing to transfer a single embryo Exclusion Criteria: * Patients that do not meet the clinical requirements for an embryo transfer per clinic standards. * Patients that desire more than a single embryo transfer. * Patients that are using a gestational carrier. * Embryonic mosaic PGT results that include chromosome errors 13, 18, 21 * Patients that did not complete their IVF with PGT cycle at the Colorado Center for Reproductive Medicine.

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Evaluation of Implantation rate

Timeframe: 3-4 weeks after embryo transfer

Live birth rate

Timeframe: 9-12 months post embryo transfer

Trial details

NCT IDNCT04472156

SponsorColorado Center for Reproductive Medicine

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2026-06-15

Contact for this trial

Rachel Makloski, RN

303-788-8300 rmakloski@colocrm.com

View on ClinicalTrials.gov More Infertility trials