CompletedNot Applicable

Advanced Glycation End Products Are Associated With Diabetic Macular Edema

Turkey (Türkiye)90 participantsStarted 2018-07-07

Plain-language summary

Diabetic macular edema can develop at all stages of diabetic retinopathy, causing visual impairment and blindness. Modern diets are high in advanced glycation end products (dAGEs), derived from processing methods, exerting a pivotal role in promoting diabetic retinopathy risk. In this cross-sectional study, we investigate the relationship between dietary and serum levels of AGEs and DME in type 2 diabetic subjects.

Who can participate

Age range18 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Included from the study were those over the age of 18 years, with diagnosis of Type 2 DM. Exclusion Criteria: * Excluded from the study were those under the age of 18 years, with no diagnosis of Type 2 DM, without any anti-diabetic agent, with any disease other than DME and DR that may affect the retina, with any disease that may affect the retina for the control group, with corneal, lens or vitreous opacification preventing Optical coherence tomography (OCT) withdrawal, with any systemic disease other than DM and hypertension, with a history of eye surgery, and with blindness or infection in the eye, along with those recently diagnosed with diabetes (\<1 year) and those with special diets.

What they're measuring

We hypothesize that the AGEs levels of the DME group would found be higher than in the control group.

Timeframe: 3 months

We hypothesize that the dietary intake of AGEs wolud be higher in the DME group.

Timeframe: 1 month

We hypothesize that neck circumference correlated significantly with DME.

Timeframe: 1 month

Trial details

NCT IDNCT04468152

SponsorHacettepe University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2019-01-10

View on ClinicalTrials.gov More Diabetic Macular Edema trials

Plain-language summary

Who can participate

Age range18 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

What they're measuring

We hypothesize that the AGEs levels of the DME group would found be higher than in the control group.

Timeframe: 3 months

We hypothesize that the dietary intake of AGEs wolud be higher in the DME group.

Timeframe: 1 month

We hypothesize that neck circumference correlated significantly with DME.

Timeframe: 1 month