Laser Treatment of Moderate to Severe Acne Vulgaris (NCT04466527) | Clinical Trial Compass
TerminatedNot Applicable
Laser Treatment of Moderate to Severe Acne Vulgaris
Stopped: Arm 2 (focal/localized treatment of 1-3 lesions, single treatment) was not initiated as resources and recruitment were prioritized for Arm 1.
United States4 participantsStarted 2020-11-09
Plain-language summary
The goal of this clinical trial is to learn if fractional ablative laser can treat active acne vulgaris in adults 18 to 40 years old with moderate to severe acne vulgaris.
The main questions it aims to answer are:
Does ablative fractional carbon dioxide treatment effectively treat moderate to severe active nodular acne vulgaris?
Does ablative fractional carbon dioxide treatment effectively treat moderate to severe active nodular acne vulgaris over a short time frame?
Is non-selective laser useful in treating inflammatory skin disease?
How does the microbiome change after laser treatment?
Participants will...
* Receive up to 3 laser treatments
* Attend a baseline visit and follow-up visits post-treatment where participants will receive a clinical assessment, facial swab, and facial-imaging
Who can participate
Age range
18 Years – 40 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion criteria
. Subject must be able and willing to provide written informed consent and comply with the requirements of the study protocol;
. In good general health, based on answers provided during the screening visit;
. Subject must be able to read and understand English;
. Any gender and any Fitzpatrick skin type;
. Ages 18 through 40;
. Subjects must have moderate to severe nodular active facial acne vulgaris (PGA 3 or 4)
. Willing to sun protect treated area for the duration of enrollment in the study and 1 year after treatment;
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.