Scleral Buckling for Retinal Detachment Prevention in Genetically Confirmed Stickler Syndrome

Inclusion Criteria: * Genetically confirmed Stickler Syndrome * Aged 5 to 35 * Recent retinal detachment in the non-study eye (\<24 months) * Signed informed consent to participate in the study; For the minors, information and consent of the holders of parental authority * Sufficient patient cooperation to perform a complete ophthalmologic examination including a dilated fundus examination * Patients affiliated with social security or CMU (profit or being entitled) Exclusion Criteria: * • Any type of previous prevention (laser, cryotherapy, scleral buckle) for the study eye * Subclinical retinal rhegmatogenous detachment in the study eye. * Any other ocular disease unrelated to Stickler syndrome significantly affecting visual acuity (ETDRS BCVA\<20/400). * Contraindications to general anesthesia * Posterior vitreoretinal traction on optical coherence tomography * Pregnant or breastfeeding women * Any patient presenting an intraocular pressure during the inclusion visit (M-3) greater than 30 mm Hg * Hypersensitivity to povidone iodine, iodine or any of the excipients of the specialty used * Hypersensitivity to acetazolamide or any of the excipients of the specialty used * Severe hepatic, renal or adrenal insufficiency * Sulfonamide intolerance * History of renal colic * Pre-existing plasma hyperosmolarity * Predominantly intracellular dehydration * Hypersensitivity to dexamethasone or any of the excipients of the specialty used * Hypersensitivity to oxytetracycline or to an…