CompletedNot Applicable

Non-invasive Assessment of the Current State of Hydration in Children by Ultrasound

Czechia30 participantsStarted 2020-09-01

Plain-language summary

Children with clinical signs of severe dehydration will be examined by ultrasound in a supine position during admission. Children aged between 1 and 15years will be divided into three weight groups: 10-20kg, 20-30kg, 30-50kg. Early after admission 1st measurement of diameters of vena cava inferior (VCImax, VCImin) during breathing cycles and diameters of both venae jugulares (VJI dx max, min, VJI sin max, min) before and after passive leg raise maneuver will be recorded. After a defined fluid infusion within 60 minutes, a second examination will be evaluated and compared with the first one. The investigators considered also echocardiography to measure CO changes however they wanted to make it as simple as it might be at emergency during the night shift without an experienced cardiologist.

Who can participate

Age range

1 Year – 15 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * previously healthy children * history and clinical signs of dehydration (gastroenteritis, diabetic ketoacidosis) Exclusion Criteria: * congenital heart diseases * intestinal obstruction * any signs of abdominal hypertension * any illnesses known to affect the volume status

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Change in vena cava inferior diameter pre- and post-hydration

Timeframe: 60 minutes

Change in vena jugularis interna diameter pre- and post-hydration (on the right side)

Timeframe: 60 minutes

Change in vena jugularis interna diameter pre- and post-hydration (on the left side)

Timeframe: 60 minutes

Change in collapsibility index pre- and post-hydration

Timeframe: 60 minutes

Trial details

NCT IDNCT04463082

SponsorUniversity Hospital Ostrava

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2021-09-01

View on ClinicalTrials.gov More Gastroenteritis trials

Plain-language summary

Who can participate

Age range

1 Year – 15 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

What they're measuring

Change in vena cava inferior diameter pre- and post-hydration

Timeframe: 60 minutes

Change in vena jugularis interna diameter pre- and post-hydration (on the right side)

Timeframe: 60 minutes

Change in vena jugularis interna diameter pre- and post-hydration (on the left side)

Timeframe: 60 minutes

Change in collapsibility index pre- and post-hydration

Timeframe: 60 minutes