CompletedNot Applicable

Effect of Cannula Size on Oxygen Saturation During Nasal High Flow Therapy in Newborns

Armenia25 participantsStarted 2020-06-26

Plain-language summary

Treatment with nasal high flow therapy (NHF) is an increasingly popular method of respiratory support in newborns. Safe and effective use of NHF requires selection of an appropriate nasal prong-to-nares ratio because leak can influence the delivered pressure. To the best of our knowledge, this is the first study to investigate the effect of using different NHF cannula size on peripheral oxygen saturation in newborns with respiratory distress.

Who can participate

Age range1 Hour – 2 Days

SexALL

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Inclusion criteria

✓. Term and near term newborns with respiratory distress receiving treatment with NHF
✓. ≤ 48 hours old
✓. FiO2 ≥ 0,4
✓. Written parental informed consent

Exclusion criteria

✕. Infants who are clinically unstable and unsuitable for non-invasive respiratory support as judged by consultant clinician (meet nHF failure criteria).
✕. Known major upper airway, lower respiratory tract, cardiac or gastrointestinal tract anomaly
✕. A parent has not given written informed consent to their baby's participation.
✕. Prior intubation and/or surfactant administration
✕. Known or suspected hypoxic ischemic encephalopathy

What they're measuring

Peripheral oxygen saturation (SpO2 )

Timeframe: 1.5 hour

Trial details

NCT IDNCT04459429

SponsorErebouni Medical Center

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2020-12-24

View on ClinicalTrials.gov More RDS - Infants trials