Impact of PH Values of the Embryo Culture Medium on Success of in Vitro Fertilization (IVF)

Inclusion Criteria: * Couples whose woman is 18 to 40 years old and man is 18 to 60 at the time of inclusion. * Infertile couple with a medical indication of IVF-ICSI according to criteria applied in each center. * First or second ICSI attempt with fresh embryo transfer. * Signature of informed consent by both partners of the couple * Affiliation to a social security scheme or equivalent for both partners of the couple. * Fitting the inclusion criteria for IVF according the the French law. Exclusion Criteria: * Use of spermatozoa extracted by testicular biopsy. * Freeze-al strategy (without fresh embryo transfer) decided before embryo culture * Absence of mature oocyte (metaphase II) at the day of the puncture * Uterine pathology affecting implantation (uterine malformation, diffuse adenomyosis ...) * One of the two partners (or both) is (are) infected with HIV, HCV or HBV in the year before the inclusion * One of the two partners (or both) is (are) in safeguarding justice, under guardianship or trusteeship. * Couple having already participated once in the study. * Couple enrolled in another interventional clinical study