UnknownNot Applicable

Testing the Noradrenergic Hypothesis of Transcutaneous Vagus Nerve Stimulation

United States55 participantsStarted 2020-09-01

Plain-language summary

This study investigates the capacity of non-invasive vagus nerve stimulation, applied at the ear, to alter to measures of locus coeruleus output pupil diameter and EEG alpha power. Non-invasive alteration in locus coeruleus output is of interest in regard to basic science and has potential clinical implications in a number of conditions.

Who can participate

Age range18 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Healthy, 18 years of age or older. Exclusion Criteria: * self-report of mood disorders, prescription and non-prescription drug use which includes stimulants including caffeine and nicotine

What they're measuring

Pupil Diameter

Timeframe: Within single one hour session

EEG Alpha power.

Timeframe: Within single one hour session

Trial details

NCT IDNCT04455295

SponsorArkansas Tech University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2025-06-01

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