Using Advanced Imaging Studies to Develop a Profile of High-grade Serous Ovarian Cancer

Inclusion Criteria: * ≥ 18 years of age or older * Histologically confirmed or clinically suspected FIGO stage IIIC-IV HGSOC * Signed consent to MSK Institutional tissue banking protocol IRB# 06-107 and signed or planned to sign IRB# 12-245, and planned to undergo multi-region tissue collection \[under the above IRB protocols\] and plan to undergo subsequent tissue analysis under biospecimen IRB# 15-200. * Staging standard-of-care contrast-enhanced CT of abdomen and pelvis (+/-chest) available in picture archiving and communication system (PACS) that was obtained at our institution as a part of standard-of-care work-up or submitted for from the outside * Plasma glucose ≤200 mg/dL * Negative pregnancy test, if a patient is of child-bearing potential Exclusion Criteria: * Known allergy to gadolinium-based contrast medium requiring premedication or known adverse reactions to gadolinium-based contrast medium. * Known history of impaired renal function, with documented eGFR \<30 within 30 days prior to PET/MRI. * Patients who cannot give valid informed consent because of general medical or physical condition, or physiologic status unrelated to presence of ovarian cancer * Patients who are unwilling or unable to undergo PET/MRI including patients with absolute or relative contraindications to MRI including breast tissue expanders, cardiac pacemakers and defibrillators, non MRI-compatible aneurysm clips, neurostimulators, programmable CSF shunts, vascular stents, claustrophobia, …