CompletedNot Applicable

ProtocoL for GFR Measurement Using Iohexol (SCOPE-PLUS) - A Substudy of the SCOPE Study

Austria, Italy, Netherlands100 participantsStarted 2019-08-08

Plain-language summary

SCOPE-PLUS is an optional substudy of the observational SCOPE Study (Screening for Chronic Kidney Disease among Older People across Europe, NCT02691546). The objective of the SCOPE-PLUS study is to derive new equations based on innovative and novel biomarkers of CKD function and compare its accuracy to measure GFR in the population older than 75 years.

Who can participate

Age range75 Years

SexALL

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Inclusion Criteria: * to be eligible for this study, subjects must have been enrolled in the SCOPE study Exclusion Criteria for substudy: * a thyroid-stimulating hormone level less than 0.3 mlU/L * a known iodine allergy * oedema * ascites * clinically symptomatic heart failure

What they're measuring

To measure GFR in subjects aged 75 or older by iohexol clearance to verify the accuracy of equations of innovative and novel biomarkers of CKD newly evaluated in the SCOPE study

Timeframe: 300 minutes from intravenous injection of iohexol

Trial details

NCT IDNCT04449172

SponsorIstituto Nazionale di Ricovero e Cura per Anziani

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2021-08-30

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