CompletedNot Applicable

Association Between Lumbar Muscle Atrophy, Sagittal Pelvic Alignment and Stenosis Grade in Patients With Degenerative Lumbar Spinal Stenosis

Switzerland165 participantsStarted 2020-02-03

Plain-language summary

This study is to evaluate the correlation between muscle atrophy (MA), sagittal alignment, and stenosis degree in patients with lumbar spinal Stenosis (LSS). From existing radiological images, specific radiographic parameters will be extracted. General Information (Age, sex, levels of stenosis, duration of symptoms) will be extracted from patient files.

Who can participate

Age range18 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Diagnosis of degenerative lumbar spinal stenosis * Upright standing sagittal plane X-ray of lumbar spine with clear visibility of pelvis sacrum and femoral head * MRI of the lumbar region with clear visibility of different muscle atrophy grade * Consent that health related information can be used for research was signed Exclusion Criteria: * Other spinal disease such as severe scoliosis, fracture, spondylolisthesis and ankylosing spondylitis. * Neuromuscular diseases such as M.Parkinson or multiple sclerosis * Previous surgery of the spine * Infection and/or malignancy tumor with involvement of the bony or soft tissue structures of the spine * Presence of a documented consent dissent.

What they're measuring

Severity of muscle atrophy (MA) from supine Magnetic Resonance Imaging (MRI) of lumbar spine

Timeframe: single time-point at baseline

Pelvic incidence (PI): Pelvic alignment from standard upright standing sagittal plane X-ray of lumbar spine with clear visibility of pelvis sacrum and femoral heads

Timeframe: single time-point at baseline

Severity of stenosis from supine MRI of lumbar spine

Timeframe: single time-point at baseline

Pelvic tilt (PT): Pelvic alignment from standard upright standing sagittal plane X-ray of lumbar spine with clear visibility of pelvis sacrum and femoral heads

Timeframe: single time-point at baseline

Sacral slope (SS): Pelvic alignment from standard upright standing sagittal plane X-ray of lumbar spine with clear visibility of pelvis sacrum and femoral heads

Timeframe: single time-point at baseline

Lumbar lordosis (LL): Pelvic alignment from standard upright standing sagittal plane X-ray of lumbar spine with clear visibility of pelvis sacrum and femoral heads

Timeframe: single time-point at baseline

Trial details

NCT IDNCT04444739

SponsorUniversity Hospital, Basel, Switzerland

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2020-09-30

View on ClinicalTrials.gov More Lumbar Spinal Stenosis (LSS) trials

Plain-language summary

Who can participate

Age range18 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

What they're measuring

Severity of muscle atrophy (MA) from supine Magnetic Resonance Imaging (MRI) of lumbar spine

Timeframe: single time-point at baseline

Pelvic incidence (PI): Pelvic alignment from standard upright standing sagittal plane X-ray of lumbar spine with clear visibility of pelvis sacrum and femoral heads

Timeframe: single time-point at baseline

Severity of stenosis from supine MRI of lumbar spine

Timeframe: single time-point at baseline

Pelvic tilt (PT): Pelvic alignment from standard upright standing sagittal plane X-ray of lumbar spine with clear visibility of pelvis sacrum and femoral heads

Timeframe: single time-point at baseline

Sacral slope (SS): Pelvic alignment from standard upright standing sagittal plane X-ray of lumbar spine with clear visibility of pelvis sacrum and femoral heads

Timeframe: single time-point at baseline

Lumbar lordosis (LL): Pelvic alignment from standard upright standing sagittal plane X-ray of lumbar spine with clear visibility of pelvis sacrum and femoral heads

Timeframe: single time-point at baseline