UnknownPhase 4

Lignocaine Nebulization for Attenuation of Intubation Stress Response

Egypt100 participantsStarted 2021-02-24

Plain-language summary

To study the effect of lignocaine nebulization on attenuation of the pressor response during induction and emergence of anesthesia in patients with severe pre-eclampsia

Who can participate

Age range18 Years – 45 Years

SexFEMALE

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * American Society of Anesthesiologist (ASA) II , III with severe pre-eclampsia * Scheduled for caesarean deliveries under general anesthesia Exclusion Criteria: * severe obesity (BMI ≥ 40 ) * Cardiac patients * History of diabetes * Renal dysfunction (Elevated creatinine ≥ 2 mg\\dl) * Hepatic dysfunction (Elevated hepatic enzymes three times above normal value) * Known fetal anomalies

What they're measuring

Systolic, diastolic, mean arterial blood pressure

Timeframe: Preoperative-Intraoperative

Heart rate

Timeframe: Preoperative-Intraoperative

Peripheral oxygen saturation

Timeframe: Preoperative-Intraoperative

Cough score during emergence

Timeframe: Up to one hour after extubation

Trial details

NCT IDNCT04441073

SponsorAssiut University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2022-02-23

Contact for this trial

Fatma N. Mohamed, M.D.

+201003633992 fatmanabil2012@gmail.com

View on ClinicalTrials.gov More Pressor Response trials