Corneal Biomechanics During Pregnancy (NCT04433689) | Clinical Trial Compass
UnknownNot Applicable
Corneal Biomechanics During Pregnancy
Switzerland50 participantsStarted 2016-01-01
Plain-language summary
It is known that intraocular pressure changes during pregnancy. Collagen structure changes during pregnancy to enable softening of the symphysis, whitening of the birth chanel, and, thus, ultimately to enable delivery of a child. The cornea consists of highly structured collagen fibers. Hence, it seams logically that corneal biomechanics also change during pregnancy.
Who can participate
Age range
18 Years – 38 Years
Sex
FEMALE
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* females
* pregnant
* age 18 to 38 yo
* uncomplicated singleton pregnancy
Exclusion Criteria:
* any history of ocular disease or surgery other than conjunctivitis, especially no history of glaucoma or corneal disease
* systemic diseases, i.e. diabetes, hypertension, collagenase
* current contact lens wear
* before pregnancy taking any systemic or ocular medications
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Change in Deformation Amplitude
Timeframe: at 3 month post delivery compared to during third trimester
2
Change in Applanation Length
Timeframe: at 3 month post delivery compared to during third trimester of the pregnancy
3
Change in Corneal Velocity
Timeframe: at 3 month post delivery compared to during third trimester of the pregnancy
4
Change in corneal thickness
Timeframe: at 3 month post delivery compared to during third trimester of the pregnancy
5
Change in Intraocular pressure
Timeframe: at 3 month post delivery compared to during third trimester of the pregnancy