CompletedPhase 1/2

Fertility Restoration Using Autologous Mesenchymal Stem Cells

Belarus10 participantsStarted 2020-10-01

Plain-language summary

Treatment of the patients with scarring and adhesions in the uterus resulting from caesarean section or chronic inflammation in the mucosa of the uterus and fallopian tubes and preventing the occurrence of these effects in the future

Who can participate

Age range

18 Years – 45 Years

Sex

FEMALE

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * chronic endometritis * postoperative uterus scars * uterine synechia * fallopian tube obstruction * absence of acute inflammation in the uterus Exclusion Criteria: * Patients with genetic diseases of muscle and connective tissue; * Patients with malformations of the uterus; * Acute and chronic infectious diseases: HIV, mycoplasma infection, hepatitis B and C, syphilis; autoimmune diseases; oncological diseases; continuous hormonal therapy with cytostatics corticosteroids; acute noncommunicable diseases; * mental disorders; * Drug or alcohol addiction; * Benign tumors of uterus and appendages; * Hypersensitivity to any component of the studied biomedical cell product.

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Number of cured patients

Timeframe: 6 months

Number of patients with treatment-related adverse events

Timeframe: 4 weeks

Trial details

NCT IDNCT04432467

SponsorInstitute of Biophysics and Cell Engineering of National Academy of Sciences of Belarus

Sponsor typeOTHER_GOV

Study typeINTERVENTIONAL

Primary completion2021-09-30

View on ClinicalTrials.gov More Chronic Endometritis trials