CompletedPhase 1/2

Fertility Restoration Using Autologous Mesenchymal Stem Cells

Belarus10 participantsStarted 2020-10-01

Plain-language summary

Treatment of the patients with scarring and adhesions in the uterus resulting from caesarean section or chronic inflammation in the mucosa of the uterus and fallopian tubes and preventing the occurrence of these effects in the future

Who can participate

Age range18 Years – 45 Years

SexFEMALE

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * chronic endometritis * postoperative uterus scars * uterine synechia * fallopian tube obstruction * absence of acute inflammation in the uterus Exclusion Criteria: * Patients with genetic diseases of muscle and connective tissue; * Patients with malformations of the uterus; * Acute and chronic infectious diseases: HIV, mycoplasma infection, hepatitis B and C, syphilis; autoimmune diseases; oncological diseases; continuous hormonal therapy with cytostatics corticosteroids; acute noncommunicable diseases; * mental disorders; * Drug or alcohol addiction; * Benign tumors of uterus and appendages; * Hypersensitivity to any component of the studied biomedical cell product.

What they're measuring

Number of cured patients

Timeframe: 6 months

Number of patients with treatment-related adverse events

Timeframe: 4 weeks

Trial details

NCT IDNCT04432467

SponsorInstitute of Biophysics and Cell Engineering of National Academy of Sciences of Belarus

Sponsor typeOTHER_GOV

Study typeINTERVENTIONAL

Primary completion2021-09-30

View on ClinicalTrials.gov More Chronic Endometritis trials