The TAPS Trial - Fetoscopic Laser Surgery for Twin Anemia Polycythemia Sequence

Inclusion Criteria: * Monochorionic twin pregnancy complicated by either spontaneous or post-laser twin anemia polycythemia sequence (TAPS), stage ≥ 2, diagnosed between 20+0 and till 28+0 weeks of gestation * Women aged 18 years or more, who are able to consent. * Written informed consent to participate in this randomized controlled trial, forms being approved by the Ethical Committees. Exclusion Criteria: * TAPS stage 1 * TAPS stage≥ 2, diagnosed within 1 week after laser surgery for twin-twin transfusion syndrome (TTTS) (a large inter-twin middle cerebral artery peak systolic velocity difference within a week after laser for TTTS is likely to related to hemodynamic reequilibration, and is usually not based on TAPS) * Triplet pregnancies, or higher order multiple pregnancies * TAPS cases that already underwent an intrauterine treatment (with the exception of laser surgery for TTTS in post-laser TAPS cases) * Congenital abnormalities (including severe cerebral injury) in one or both twins