CompletedNot Applicable

In-Utero Vascular Accidents in Neonates From COVID-19 Infected Mothers

United States215 participantsStarted 2020-08-18

Plain-language summary

The pregnancy related pro-thrombotic state, in addition to the COVID-19 associated hypercoagulability may have unknown consequences to the developing fetus. Hence, this proposal seeks to address this question that may have important implications for women that contract this virus during gestation.

Who can participate

Age range18 Years

SexALL

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Inclusion Criteria: * Pregnant females, 18 years and higher, with documented COVID-19 infection (antigen, PRC, or antibodies in a biologic sample) during gestation who received medical care at the University of Colorado Hospital (UCH) or Children's Hospital Colorado (CHCO) * Neonates born to COVID-19 infected mothers * Neonates ages 1-60 days of life with documented limb anomalies and intestinal atresias Exclusion Criteria: * Mothers with a history of vasoactive drug usage during pregnancy * Mothers taking known teratogens during pregnancy

What they're measuring

Rates of intestinal atresias and limb abnormalities

Timeframe: 12 months

Rates of preterm labor, fetal growth restriction and spontaneous abortions

Timeframe: 12 months

Rates of maternal SARS-CoV-2 infection among mothers to infants born with intestinal atresias or limb anomalies

Timeframe: 12 months

Trial details

NCT IDNCT04431869

SponsorUniversity of Colorado, Denver

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2021-09-01

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