TerminatedNot Applicable

PERSEUS-PS Randomized Controlled Trial

Stopped: The trial prematurely terminated as a result of the COVID-19 pandemic.

Greece14 participantsStarted 2020-06-12

Plain-language summary

The PERSEUS protocol is a new approach to the resuscitation of highly monitored patients with cardiac arrest. It aims at the optimization of all the available physiological parameters and the full exploitation of both the "cardiac pump" and "thoracic pump'. This protocol will help to titrate chest compressions, ventilation, and vasopressor dosing to physiological parameters, increasing survival after cardiac arrest with favorable neurological outcome

Who can participate

Age range18 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * invasive arterial blood pressure monitoring prior to and during CPR * first compression of CPR captured on transmitted arterial blood pressure waveform data * internal jugular or subclavian central venous catheter prior to and during CPR * patients with measurement of systemic vascular resistance prior to and during CPR Exclusion Criteria: * unable to determine any of the aforementioned parameters during CPR * unable to determine when CPR started and stopped * subjects within the exclusion period of another study

What they're measuring

ROSC

Timeframe: From start of CPR until return of spontaneous circulation, assessed up to 60 minutes

Trial details

NCT IDNCT04428060

SponsorUniversity of Thessaly

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2022-12-30

View on ClinicalTrials.gov More Cardiac Arrest trials