Visual Surround Suppression and Perceptual Expectation Under Psilocybin

Inclusion Criteria: * Have given written informed consent * Have at least a high-school level of education or equivalent (e.g. GED), and be able to read and write in English * General health status: Participants should be in good physical (BMI between 20.0 and 28.0 kg/m2) and psychiatric health. * Experience taking psilocybin (at the PI's discretion). * Participants must also have a person that can reliably transport them to and from the CRU for dosing session days. * Geographic location: Minnesota counties that are approximately within 1 hour driving distance to Twin Cities, including not limited to Hennepin, Ramsey, Washington, Anoka, Wright, Carver, Scott, Dakota, Sherburn * Participants must be willing to wear a face mask at all times during in-person study visits, except for dosing sessions, to ensure COVID-19 protection. * Participants must be willing to get a COVID-19 test and share results with the study team prior to all in-person visits. * Participants must be up-to-date on COVID-19 vaccines, per CDC guidelines, and share a copy of their proof of vaccination status with the study team prior to the consenting visit. * Agrees to refrain from using recreational drugs while enrolled in the study, including, but not limited to, hallucinogens, ketamine, and marijuana. Exclusion Criteria: * Current or past history of meeting DSM-5 criteria for schizophrenia spectrum or other psychotic disorders (except due to another medical condition), or Bipolar I or II Disorder, pers…