RecruitingNot Applicable

Functional Changes in the Stomach and Esophagus After One Anastomosis Gastric Bypass- OAGB

Switzerland300 participantsStarted 2020-06-01

Plain-language summary

Evaluation of the functional changes in the stomach and esophagus of patients undergoing One Anastomosis Gastric Bypass (OAGB)

Who can participate

Age range18 Years – 65 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * BMI\> 35 kg/m2 * 2 years of controlled conservative obesity treatment without weight reduction * patients should give their consent to participate in the study Exclusion Criteria: * Less than 2 years of conservative obesity treatment * cancer * cirrhosis Child-Pough score A * Crohn's disease * serious psychiatric disorder, which led to in-hospital treatment in psychiatric clinic in the past two years * drug consumption * non-compliance * hiatal hernia \> 4cm * gastric pouch \< 10cm * Barett esophagus * erosive esophagitis Grade C or D according to the Los Angeles Classification * endoscopically proven gastric stricture * acid exposition time \> 6% (Lyon criteria) * reflux episodes\> 80 /24 hours (Lyon criteria) * insufficient low esophageal sphincter according to manometry findings * pathological findings in the impedance pH-metry (acid and non-acid reflux)

What they're measuring

Marginal ulcer rates

Timeframe: 2 years post surgery

Marginal ulcer rates

Timeframe: 5 years post surgery

Assessment of age as risk factor for marginal ulcer development

Timeframe: 2 years post surgery

Assessment of age as risk factor for marginal ulcer development

Timeframe: 5 years post surgery

Assessment of gender as risk factor for marginal ulcer development

Timeframe: 2 years post surgery

Assessment of gender as risk factor for marginal ulcer development

Timeframe: 5 years post surgery

Assessment of tobacco use as risk factor for marginal ulcer development

Timeframe: 2 years post surgery

Assessment of tobacco use as risk factor for marginal ulcer development

Timeframe: 5 years post surgery

Trial details

NCT IDNCT04422405

SponsorSpital Limmattal Schlieren

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2035-05-28

Contact for this trial

Urs Zingg, MD, Prof.

+41 44 733 21 26 urs.zingg@spital-limmattal.ch

View on ClinicalTrials.gov More Obesity, Morbid trials

Who can participate

Age range18 Years – 65 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

What they're measuring

Marginal ulcer rates

Timeframe: 2 years post surgery

Marginal ulcer rates

Timeframe: 5 years post surgery

Assessment of age as risk factor for marginal ulcer development

Timeframe: 2 years post surgery

Assessment of age as risk factor for marginal ulcer development

Timeframe: 5 years post surgery

Assessment of gender as risk factor for marginal ulcer development

Timeframe: 2 years post surgery

Assessment of gender as risk factor for marginal ulcer development

Timeframe: 5 years post surgery

Assessment of tobacco use as risk factor for marginal ulcer development

Timeframe: 2 years post surgery

Assessment of tobacco use as risk factor for marginal ulcer development

Timeframe: 5 years post surgery