Cervical Plexus Hydrodissection With D5W for PTSD (NCT04421573) | Clinical Trial Compass
Active — Not RecruitingNot Applicable
Cervical Plexus Hydrodissection With D5W for PTSD
United States24 participantsStarted 2023-07-10
Plain-language summary
PTSD is a chronic mental health condition that drastically reduces an individual's quality of life Dextrose injection with a small needle has been used for chronic pain patients and observational results have shown it to be effective in reducing anxiety, brain fog, and depression in patients with PTSD. This randomized trial will compare dextrose injection with a delayed/usual treatment control.
Who can participate
Age range
19 Years – 90 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Not involved in another study of PTSD treatment
* Reliable transportation
* Comfortable with computers
* Tried 2 or more medications for treatment of PTSD symptoms
* Tried 2 or more non-medication treatments for PTSD symptom
* No known life-threatening illness
* Not taking daily narcotics
* Not having 3or more alcoholic drinks on an average day
* No active suicidal plans
* No major surgery plans
* No major life stress that might interfere with completing study
* Symptoms for more than 1 year
* Not planning to move for next 18 months.
* Living within an hour of Portlland, OR, Madison, WI, or Lexington, KY
* Wiling to provide 2 email and 2 phone contact methods
* Willing to answer questions on multiple occasions over the course of a year.
* Willing to be assigned to 3 months of usual care treatment
* No diagnosis of schizophrenia, Borderline Personality Disorder, or Bipolar Disorder.
* No severe needle phobia
* Chronic pain ≤ 5/10
* PCL-C score ≥ 50
Exclusion Criteria: None separate from inclusion criteria
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1This trial is measuring consent rates, data capture rates, and satisfaction — not symptom improvement or recovery — so does that mean it's mainly designed to test whether this kind of study is even feasible, rather than to prove the treatment actually works for PTSD?
2The procedure involves injecting a sugar-water solution called D5W around nerves in the neck through a technique called hydrodissection — can you explain what that physically involves, what the risks are, and whether my current health situation makes that safe for me?
3Since the trial is no longer actively recruiting, is there any way to find out if this study has produced results yet, or whether a follow-up study is planned that I might be eligible for?
4Given that this appears to be a very early feasibility study rather than a phase testing effectiveness, would it make more sense for me to explore standard PTSD treatments first, and how does this trial fit into the bigger picture of my care options?
5The trial focuses on a cervical plexus nerve block approach to PTSD — is there existing evidence outside this trial that this type of procedure has helped people with PTSD, so we can better understand what's known versus what's still experimental?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.