The Precise Selection of Stent Diameter for Portal Hypertension Patients With TIPS

Criteria: Inclusion Criteria: * age 18-75 years; * high-risk treatment failure (e.g.Child-Pugh C or B grade with variceal bleeding); * conventional drugs and endoscopic treatment of esophageal variceal bleeding are not good; * End-stage liver disease with variceal bleeding before liver transplantation; * successful implementation of TIPS; * good compliance with the requirements formulated by the study; * with written informed consent. Exclusion Criteria: * Liver transplantation in the past or planning liver transplantation in the 6 months; * Common TIPS contraindications (e.g.NYHA level 2 of congestive heart failure ,history of pulmonary hypertension, portal vein trunk thrombosis, multiple liver cysts,or intrahepatic bile duct dilatation); * severe liver dysfunction: prothrombin activity \<40% or bilirubin\> 50μmol / L or Child-Pugh score\> 12; * history of hepatic encephalopathy; * serum creatinine\> 133μmol / L; * severe hyponatremia (blood sodium \<125mmol / L); * uncontrollable infections; * allergic to intravenous contrast agent; * subject refused to participate in the trial or without the ability to participate in informed consent; * previous history of TIPS treatment; * any comorbidities or conditions that affect the test results as judged by the investigator.