CompletedNot Applicable

Histological, Genetic and Epigenetic Analysis of Procedures Related with Dental Implants

Spain200 participantsStarted 2019-01-29

Plain-language summary

In this study genomic, proteomic and histological technologies for the search and characterization of epigenetic modifications and molecular or protein markers, useful in the diagnosis and progression of peri-implant diseases and prevention of implant failure will be used.

Who can participate

Age range20 Years – 90 Years

SexALL

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Inclusion criteria

✓Subjects do not have or have had a history of periodontal disease, as described in the " 2017 World Workshop on the Classification of Periodontal and Peri- Implant Diseases and Conditions "
✓Samples of subjects who have at least one implant - supported prosthesis for at least 12 months and affected by peri- implant disease according to the " 2017 World Workshop on the Classification of Periodontal and Peri-Implant Diseases and Conditions "

What they're measuring

Differences in histological characteristics in peri-implantitis subjects compared to healthy subjects, ie, presence and amount of inflammatory cells and bacteria.

Timeframe: 1 day

Differences in epigenetic characteristics analyzing DNA methylation in peri-implantitis subjects compared to healthy subjects.

Timeframe: 1 day

Trial details

NCT IDNCT04421066

SponsorSimón Pardiñas López

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2021-10-21

View on ClinicalTrials.gov More Peri-Implantitis trials