Effects of Preferential Left Ventricular Pacing on Ventriculoarterial Coupling and Clinical Course of Heart Failure

Exclusion criteria

• ✕. Have an existing Class I recalled lead,
• ✕. Are anticipated to need heart transplantation within the next 9 months,
• ✕. Have undergone cardiac transplantation less than 40 days prior to enrolment,
• ✕. Have had a cerebrovascular accident or transient ischemic attack within 3 months of enrollment,
• ✕. Have had a recent myocardial infarction less than 40 days prior to enrollment, or unstable angina or cardiac revascularization less than 3 months prior to enrolment,
• ✕. Have documented moderate to severe/severe mitral/aortic/tricuspid/pulmonary insufficiency (noninvasive VAC calculation impossible),
• ✕. Exhibit a daily burden of premature ventricular complexes (PVCs) of either ≥10% of total QRSs or ≥10,000 on ambulatory ECG recording21, 22 (to exclude PVC-related, potentially reversible cardiomyopathy),
• ✕. Are currently participating in a clinical investigation that includes an active treatment arm,