The InterSat Study

Inclusion Criteria: * Healthy (free of diagnosed diseases listed in exclusion criteria). * Able to give informed consent. * Able to give informed consent. * Accessible veins on arms as determined by examination at screening Exclusion Criteria: * Having a medical condition or history which might impact study measurements, to be judged by the study physician (e.g. myocardial infarction, angina, thrombosis, stroke, cancer, liver or bowel disease or diabetes) * Use of plant-sterol/stanol-enriched foods or supplements in the three months prior to the screening and/or during the study * Body mass index \< 20 kg/m2 or \> 35 kg/m2 * Plasma cholesterol ≥7.5 mmol/L * Plasma triacylglycerol \> 3 mmol/L * Plasma glucose \> 7 mmol/L * Full blood count (FBC), liver function out of healthy range * Blood pressure ≥140/90 mmHg * Current use of antihypertensive or lipid lowering medications * Use of over-the-counter and prescribed medication, which may interfere with study measurements (to be judged by the principal investigator) * Alcohol intake exceeding a moderate intake (\> 21 units per week) * Current cigarette smoker (or quit within last 6 months) * ≥ 20% 10-year risk of cardiovascular disease (CVD) as calculated using a risk calculator * Active blood donor or plans to donate blood within 6 months of study completion * Use of oral antibiotics (with the exception of topical antibiotics) in 40 days or less prior to the start of the study * Reported weight loss or gain of 3 kg or more du…