UnknownNot Applicable

EEG Patterns in Patients With Acute Ischemic Stroke Resulted From Large Vessels Occlusion in the Anterior Circulation

Israel200 participantsStarted 2020-10-04

Plain-language summary

Clinical deterioration is observing in up to forty percent of patients with acute ischemic stroke (AIS) due to large vessels occlusion. Until now, there is no automated monitoring system for early detection of neurological deterioration in such patients. As a first step to develop such system investigators suggest this study aiming to evaluate patterns of brain electrical activity registered by EEG in patients with AIS attributed to the MCA or ICA territory correlated with location and extension of ischemic lesions as determined by non-contrast CT (NCT).

Who can participate

Age range

18 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Patients with acute ischemic stroke, due to large vessel occlusion * Age of 18 years and more * Male or Female * Modified Rankin Scale of ≤ 2 prior to presentation * NIHSS ≥ 4 at the day of NCT and EEG Exclusion Criteria: * Epilepsy * Brainstem or cerebellar stroke * Intracranial or extracranial hemorrhage of any kind * History of severe head trauma * History of severe dementia or progressive neurodegenerative disease * Cerebral tumor or hydrocephalus by anamnesis or by imaging * Lacunar stroke * Significant movement disorder. * Local skull or skin condition, preventing EEG electrode application. * Any known disorder, which may interfere with the protocol implementation.

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

EEG pattern

Timeframe: 24 months

Trial details

NCT IDNCT04412434

Sponsorrambam62

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2022-07

Contact for this trial

Gregory Telman, MD

972-47772161 g_telman@rmc.gov.il

View on ClinicalTrials.gov More Stroke, Ischemic trials