CompletedNot Applicable

Colloid Co-hydration and Vasoconstrictor Infusion for Prevention of Hypotension During Cesarean Section

Greece120 participantsStarted 2020-05-23

Plain-language summary

This will be a double-blind randomized study, aiming at investigating a fixed rate phenylephrine infusion versus a fixed rate norepinephrine infusion versus placebo in combination with co-hydration with colloids for the prevention of maternal hypotension in elective cesarean section

Who can participate

Age range18 Years – 48 Years

SexFEMALE

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * adult parturients, American Society of Anesthesiologists (ASA) I-II, * singleton gestation\>37 weeks * elective cesarean section Exclusion Criteria: * Body Mass Index (BMI) \>40 kg/m2 * Body weight \<50 kg * Body weight\>100 kg * height\<150 cm * height\>180 cm * multiple gestation * fetal abnormality * fetal distress * active labor * cardiac disease * pregnancy-induced hypertension * thrombocytopenia * coagulation abnormalities * use of antihypertensive medication during pregnancy * communication or language barriers * lack of informed consent * contraindication for regional anesthesia

What they're measuring

incidence of bradycardia

Timeframe: intraoperative

incidence of hypotension

Timeframe: intraoperative

Trial details

NCT IDNCT04404946

SponsorAretaieion University Hospital

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2021-05-31

View on ClinicalTrials.gov More Hypotension Symptomatic trials