CompletedNot Applicable

Study of Opioid-Induced Constipation 2 Project

United Kingdom100 participantsStarted 2017-08-21

Plain-language summary

The aim of the project is to investigate OIC in a real world / diverse group of patients with cancer. The objectives of the project are to determine: a) efficacy of a treatment algorithm to manage OIC; b) efficacy of conventional laxatives to manage OIC; c) efficacy of PAMORAs / other interventions to manage OIC.

Who can participate

Age range18 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * As per StOIC 1: age \> 18yr; diagnosis of cancer; diagnosis of cancer pain; receipt of regular opioids for at least one week * Diagnosis of OIC as defined by the Rome IV criteria (Lacy et al, 2016) * Diagnosis of inadequately treated OIC as defined by BFI \> 30 Exclusion Criteria: * As per StOIC 1: inability to give informed consent; inability yo complete questionnaire * Prognosis \> 1 month

What they're measuring

Resolution of OIC

Timeframe: 28 days

Trial details

NCT IDNCT04404933

SponsorRoyal Surrey County Hospital NHS Foundation Trust

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2019-08-30

View on ClinicalTrials.gov More Opioid-induced Constipation trials