RecruitingNot Applicable

Serological and PCR Testing for COVID-19

United Kingdom2,500 participantsStarted 2020-03-16

Plain-language summary

Richmond Research Institute (RRI) is applying existing and new COVID-19 PCR and antibody tests to help develop methodologies which provide fast and accurate results. Infection with coronavirus (SARS-CoV-2) is currently a worldwide pandemic and reliable testing for COVID-19 is crucial to understand who is infected and therefore a risk to others by spreading the infection. RRI are currently carrying out the following tests: A. Using a membrane-based immunoassay to detect IgG and IgM antibodies to SARS-CoV-2 in whole blood, serum or plasma specimens helps to assess whether an individual has previously had the virus and is potentially immune B. Polymerase Chain Reaction (PCR) testing using an established method to check for active SARS-CoV-2 infections. C. Quantification of anti-SARS-CoV-2 IgG and IgM antibodies in whole blood samples. The above tests are being used by RRI to follow infections (PCR) and immunity (IgG) in their workforce, as well as their families (including children) and visitors to their site. Collecting this data allows the gathering of epidemiological data on SARS-CoV-2 including incidence, prevalence, information on asymptomatic carriers and efficacy of vaccination. Furthermore, identifying individuals that are infected with SARS-CoV-2 has great potential to improve health outcomes by allowing infected individuals to seek the correct medical treatment as well as self-isolate and reduce transmission.

Who can participate

Age range

5 Years – 70 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Male or female aged 5 to 70 years. * An understanding, ability, and willingness to fully comply with the project procedures and restrictions. Exclusion Criteria: * Not applicable.

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1This study is focused on identifying carriers of SARS-CoV-2 using serological and PCR testing — does that mean it's primarily a surveillance or diagnostic study rather than a treatment trial, and how would that affect what I personally get out of participating?
2Since this trial doesn't have a listed phase, it seems to be more of an observational study — can you explain what that means for my safety and whether there are any risks associated with the testing procedures involved?
3If the goal is to detect who is carrying or has been exposed to COVID-19, will I actually receive my individual test results, and how would those results be used in my own care?
4Given that this study is still actively recruiting, is participating something that makes sense given my current health situation, or would my time be better spent focusing on treatment options right now?
5Are there any eligibility requirements for this study — like whether I need to currently have symptoms, have already recovered, or have no prior COVID-19 diagnosis — that my doctor thinks would or wouldn't apply to my situation?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Identification of carriers of SARS-CoV-2

Timeframe: Through study completion, estimated 12 weeks

Trial details

NCT IDNCT04404062

SponsorRichmond Research Institute

Sponsor typeINDUSTRY

Study typeOBSERVATIONAL

Primary completion2028-12-01

Contact for this trial

Jorg Taubel, MD

+44(0)2070425800 j.taubel@richmondpharmacology.com

View on ClinicalTrials.gov More COVID-19 trials