CompletedPhase 1/2

Chlorhexidine Vaginal Preparation for Reduction of Post-cesarean Endometritis and Sepsis

Saudi Arabia840 participantsStarted 2020-05-15

Plain-language summary

The study aims to assess the beneficial value of vaginal preparation with chlorhexidine gluconate 0.05% before cesarean delivery of cases in labor in reduction of postoperative endometritis, fever and wound complications compared to no preparation or using saline only.

Who can participate

Age range18 Years

SexFEMALE

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Inclusion criteria

✓. Gestational age ≥28 weeks.
✓. Cases had cesarean section after start of labor.

Exclusion criteria

✕. Women with known allergy to chlorhexidine gluconate or any of its ingredients.
✕. Women with diagnosed group B streptococcus (GBS) colonization.
✕. Women with active infection during the procedure.
✕. Women did not receive the standard preoperative antibiotic prophylaxis.
✕. Women with diagnosis of chorioamnionitis.
✕. Prolonged rupture of membranes \>7 days

What they're measuring

post-cesarean endometritis

Timeframe: First 10 days post-cesarean

Postoperative wound infection

Timeframe: First month after cesarean

Trial details

NCT IDNCT04385680

SponsorZagazig University

Sponsor typeOTHER_GOV

Study typeINTERVENTIONAL

Primary completion2022-03-10

View on ClinicalTrials.gov More Postpartum Endometritis trials