Combination Diagnostic Strategies in NAFLD (NCT04384159) | Clinical Trial Compass
CompletedNot Applicable
Combination Diagnostic Strategies in NAFLD
577 participantsStarted 2011-11-30
Plain-language summary
Serial combination of biological and elastography tests is accurate to diagnosing advanced fibrosis in non-alcoholic fatty liver disease (NAFLD) patients. In this study, the investigators compared the diagnostic performances of a 2-step strategy using either vibration-controlled transient elastography (VCTE) or bidimensional shear wave elastography with Supersonic imagine (2D-SWE-SSI), and analysed the added-value of a 3-step strategy.
Who can participate
Age range
18 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion criteria:
\- PAtients who underwent a liver biopsy for a suspicion of NAFLD, and liver stiffness evaluation with either Fiborscan and Bidimensional shear wave elastography
Exclusion criteria:
* Other aetiologies of chronic liver disease
* biopsy length under 10mm
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1This trial is about diagnosing NAFLD more accurately — since it's already completed, would my doctor be able to tell me what combination of diagnostic tests was found to work best, and whether those methods are now being used in my own care?
2Since this was a diagnostic study rather than a treatment trial, does it mean there's no experimental therapy involved, and if so, how might the findings from this research actually change the way my liver disease gets evaluated going forward?
3NAFLD can range widely in severity — does my doctor think the diagnostic strategies tested in this trial, like non-invasive imaging or blood markers, could help determine how advanced my condition is without needing a liver biopsy?
4Because this trial has completed, are the results published or available somewhere my doctor could review, and would those findings be relevant to how we monitor my liver health over time?
5Are there other ongoing trials or updated diagnostic protocols for NAFLD that my doctor would recommend exploring now that this study is finished, especially if I want to stay ahead of disease progression?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.