CompletedNot Applicable

Effect of Hydration Guided by Vigileo on the Prevention of CIN After PCI for Patients With AMI

China344 participantsStarted 2020-07-10

Plain-language summary

In this study, Vigileo is used to guide hydration adjustment, and SCr is used to estimate renal function. The aim of the study is to investigate the preventive effect of adequate hydration guided by Vigileo on contrast induced nephropathy in patients with acute myocardial infarction who undergo PCI.

Who can participate

Age range

18 Years – 80 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Clearly diagnosed STEMI or NSTEMI patients: * Patients aged 18-80 years * Patients are scheduled to undergo emergency percutaneous coronary interventions * Estimated glomerular filtration rate eGFR \<120ml / min (according to MDRD formula) * Sign the informed consent to join the group. Exclusion Criteria: * Patients with mechanical complications * Patients with cardiogenic shock * Patients with aortic dissection * Patients who have malignant tumors or short-term progressive diseases that researchers believe improper to be included in the group * Hemodialysis-dependent patients with end-stage renal failure * Patients who had a history of exposure to radioactive contrast media within 1 week before or 72 hours after direct PCI * Patients who are allergic to radioactive contrast agents * Patients diagnosed with right ventricular myocardial infarction with hypotension (defined as systolic blood pressure ≤90 mmHg) on admission.

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Contrast induced nephropathy

Timeframe: 48-72 hours after PCI

Trial details

NCT IDNCT04382313

SponsorChinese PLA General Hospital

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2022-05-30

View on ClinicalTrials.gov More Myocardial Infarction trials