TerminatedNot Applicable

Hypertonic Saline Nasal Irrigation and Gargling in Suspected or Confirmed COVID-19 (ELVIS COVID-19)

Stopped: Halted prematurely due to slow recruitment

United Kingdom16 participantsStarted 2020-06-23

Plain-language summary

ELVIS COVID-19 is a pragmatic web-based Bayesian adaptive randomised controlled, parallel group trial of hypertonic saline nasal irrigation and gargling (HSNIG) compared to standard care in participants with clinically suspected or confirmed COVID-19 being managed at home.

Who can participate

Age range18 Years

SexALL

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Inclusion criteria

✓. Clinical symptoms suggestive of COVID-19 (i.e. those who have at least one of the following symptoms: recent onset of (i) new continuous cough and/or (ii) high temperature) and/or (iii) loss of, or change in, sense of smell or taste (anosmia) OR
✓. Those with virologically confirmed SARS-CoV-2 infection and clinical symptoms indicative of COVID-19 (as detailed in (a) above).

What they're measuring

Time to Resolution of Symptoms as Defined by the Single Question 'How Unwell do You Feel Today'.

Timeframe: Maximum of 14 days

Trial details

NCT IDNCT04382131

SponsorUniversity of Edinburgh

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2020-10-31

Results submitted2025-09-12

View on ClinicalTrials.gov More Upper Respiratory Tract Infections trials