Interest of Tracheal Extubation in Positive Pressure on Postoperative Oxygenation in Adult Digest… (NCT04381949) | Clinical Trial Compass
CompletedNot Applicable
Interest of Tracheal Extubation in Positive Pressure on Postoperative Oxygenation in Adult Digestive Surgery
France208 participantsStarted 2022-08-03
Plain-language summary
Evaluation of a postoperative tracheal extubation protocol under positive pressure in accordance with international recommendations.
Two arms: the first with "classic" extubation with disconnection of the respirator and the second with extubation without disconnection of the respiratory, as recommended.
Computer Randomization with a 1: 1 ration
Who can participate
Age range18 Years – 80 Years
SexALL
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Inclusion Criteria:
* Age\> 18 and \<80
* Patient going to benefit from general anesthesia with orotracheal intubation for surgery lasting more than 60 minutes at the visceral surgery unit of the Rouen University Hospital.
* Person affiliated to a social security scheme
* Person who has read and understood the newsletter and signed the consent form
Exclusion Criteria:
* Minor patients or age\> 80 years
* History of Obstructive Sleep Apnea Syndrome
* Chronic respiratory failure / History of chronic obstructive pulmonary disease
* Surgery \< 60 minutes
* Use of methylene blue intraoperatively
* Extubation finally performed in the operating room
* orotracheal intubation difficult to induce general anesthesia
* Suspected inhalation during orotracheal intubation
* Pneumothorax per operative
* Heart failure authenticated by trans thoracic ultrasound \<50%
* Neuromuscular pathologies (myasthenia gravis, myopathies)
* Body mass index\> 35
* Emergency surgery
* Patient with an ASA IV score (ie according to the definition of the American Society of Anesthesiology)
* Major surgical complications (hemorrhagic shock)
* Major anesthetic complications (anaphylactic shock, bronchospasm)
* Pregnant or parturient or lactating woman or woman of childbearing age without proven contraception
* Person deprived of their liberty by an administrative or judicial decision or person placed under the protection of justice / guardianship or curatorship