CompletedNot Applicable

Ipsilateral and Contralateral Index for the Interpretation of Adrenal Vein Sampling (AVS) in Primary Aldosteronism

Italy60 participantsStarted 2005-01-01

Plain-language summary

Adrenal vein sampling (AVS) is currently considered the gold standard for subtype diagnosis of primary aldosteronism (PA). However, the percentage of unsuitable procedures due to the unsuccessful cannulation of one of the two adrenal veins is still considerable, and there is no general consensus on the criteria that should be used for the interpretation of the results of an AVS study in these specific cases.

Who can participate

Age range18 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Confirmed Diagnosis of Primary Aldosteronism * Execution of Adrenal Vein Sampling (AVS) for Subtype Diagnosis Exclusion Criteria: * Execution of AVS in stimulated condition (i.e. with cosyntropin stimulation) * Inability to achieve successful catheterization of one or both adrenal veins during AVS (as established by adrenal/peripheral vein cortisol ratio)

What they're measuring

Monolateral index for each adrenal gland in each patient

Timeframe: At AVS procedure

Aldosterone/cortisol index for each adrenal gland in each patient

Timeframe: At AVS procedure

Trial details

NCT IDNCT04378387

SponsorUniversity of Turin, Italy

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2020-04-30

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