The Rhode Island Prescription and Illicit Drug Study (NCT04372238) | Clinical Trial Compass
CompletedNot Applicable
The Rhode Island Prescription and Illicit Drug Study
United States509 participantsStarted 2020-08-31
Plain-language summary
This study will test the efficacy of a novel drug-checking intervention to prevent fatal and non-fatal overdose among people who use drugs (PWUD), who are 18-65 years old at the time of enrollment. The investigators will evaluate whether the incorporation of rapid fentanyl testing into a theory-driven overdose education and prevention intervention reduces rates of overdose compared to standard overdose education and naloxone distribution. Results from this study will significantly improve public health efforts to address the fentanyl overdose epidemic and reduce harms associated with exposure to drugs contaminated with fentanyl. This is a full clinical trial, building on the previously approved fentanyl-test-strip pilot study (2016-2017), the results of which have recently been published.(Krieger et al., 2018)
Who can participate
Age range
18 Years – 65 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Reside in Rhode Island
* Are able to complete interviews in English
* Are able to provide informed consent
* Self-report past 30 day heroin, illicit stimulants, counterfeit prescription pills, or injection drugs
Exclusion Criteria:
* Participants who exclusively misuse medications obtained from a physician or diversion from someone else's prescription
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1This study is already completed — does that mean results are available, and if so, what did they find about overdose rates among participants in Rhode Island?
2Since this study was tracking overdose events rather than testing a new treatment, would the data it collected change how you'd approach my own overdose risk or prevention plan?
3The trial focused on both prescription and illicit drug use — given my specific situation, do you think the findings from a study like this are relevant to the risks I personally face?
4Because this was an observational study with no listed phase, it wasn't testing a new drug or intervention — so should I be looking at separate treatment trials that are actively testing overdose prevention strategies?
5Were there any local Rhode Island programs or resources connected to this study that might still be available and worth considering as part of my care?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Number of People Identified Has Having One or More Overdose Among RAPIDS Trial Participants