CompletedNot Applicable

Perioperative Muscle Relaxant and Postoperative Outcomes

China999 participantsStarted 2018-03-17

Plain-language summary

Muscle relaxant is usually needed for surgery. However, the optimal depth of neuro-muscular blockade is still on debate. Deep neuro-muscular blockade may benefit the patients during surgery, but may increase the risk of residual blockade after surgery. Residual blockade has been reported to increase risk of morbidity. In this study, we tend to observe the postoperative outcomes in patients undergoing abdominal surgery under general anesthesia. And to compare the outcomes in patients received different depth of neuro-muscular blockade.

Who can participate

Age range18 Years – 100 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Age ≥18 years old * Body mass \<18 kg/m2 * American Society of Anesthesiologists status I-II * Patients scheduled for elective laparoscopic colorectal or urological surgery * Patients received general anesthesia and muscle relaxant * Patients with written informed consent. Exclusion Criteria: * Second surgery during the same admission. * Outpatient surgery * Retroperitoneal laparoscopic surgery * Patients scheduled for mechanical ventilation after surgery * Patients scheduled for muscle relaxant other than rocuronium * Patients with pregnancy or planned for breeding * Patients who are involved in other studies

What they're measuring

Visual Analogue Scale of pain at rest at 24 hours after surgery

Timeframe: from end of surgery to 24 hours after surgery

Visual Analogue Scale of pain at cough at 24 hours after surgery

Timeframe: from end of surgery to 24 hours after surgery

Trial details

NCT IDNCT04371588

SponsorAir Force Military Medical University, China

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2021-08-12