Thermoregulation Among Individuals With First-episode Psychosis (NCT04369677) | Clinical Trial Compass
WithdrawnNot Applicable
Thermoregulation Among Individuals With First-episode Psychosis
Stopped: lack of funding
United States0Started 2017-01-17
Plain-language summary
The project will evaluate thermoregulatory processes among individuals with and without first-episode psychosis.
Who can participate
Age range18 Years – 35 Years
SexALL
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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Eligibility for Individuals with First-Episode Psychosis:
1. Diagnosis of a schizophrenia-spectrum disorder or mood disorder with psychotic features as determined using the Structured Clinical Interview for the DSM-5 .
2. Less than 5 years since the onset of frank psychotic symptoms as determined using the Symptom Onset in Schizophrenia Inventory.
3. No evidence of a pre-existing intellectual disability defined as a premorbid IQ \>70 as estimated using the Reading subtest of the Wide Range Achievement Test-4.
Eligibility for Individuals without First-Episode Psychosis:
1. No diagnosis of a schizophrenia-spectrum disorder or mood disorder with psychotic features as determined using the Structured Clinical Interview for the DSM-5.
2. No evidence of a pre-existing intellectual disability defined as a premorbid IQ \>70 as estimated using the Reading subtest of the Wide Range Achievement Test-4.
Eligibility for Individuals with and without First-Episode Psychosis:
1. Ages 18 - 35
2. No evidence of swallowing difficulties as assessed using the Swallowing Disturbance Questionnaire \[SDQ\]. defined as (i) a score \<5 on the SDQ oral phase questions, (ii) a score \<11.5 on the laryngopharygeal phase SDQ questions, and a total SDQ score \< 12.5.
3. Not meeting diagnostic criteria for a substance use disorder over the past month as determined using the Structured Clinical Interview for the DSM-5 .
4. No current or past diagnosis of a medical condition known to affect thermoregulato…
What they're measuring
1
Differences in mean temperature and diurnal temperature variation
Timeframe: 24 hour intervals
2
Differences in mean temperature and temperature variation during periods of rest and activity
Timeframe: 24 hour intervals
3
Association of core body temperature and ratings of psychotic symptomatology in FEP