UnknownNot Applicable

Single Dose of Clonazepam Versus Intermiittent Diazepam for Febrile Seizures Prevention

Thailand74 participantsStarted 2020-05-13

Plain-language summary

To study the efficacy and safety of single dose clonazepam compared with intermittent oral diazepam for prevention of recurrent febrile seizures in children who had three or more febrile seizures.

Who can participate

Age range

6 Months – 60 Months

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * age 6-60 months at date of enrollment * 3 or more episodes of clinically diagnosed febrile seizures Exclusion Criteria: * history of afebrile seizures or any history suggested the epilepsy * history of previous brain insults; CNS infection, birth trauma, traumatic brain injury. * delayed developmental milestones * abnormal neurological examinations * currently treatment by continous antiepileptic drug(s) * A contraindication to Clonazepam, Diazepam such as drug hypersensitivity, liver disease. * Predictable lack of available of follow up.

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Recurrent rate of febrile seizures

Timeframe: the assessment will be done at 12 months after enrollment

Trial details

NCT IDNCT04364321

SponsorQueen Sirikit National Institute of Child Health

Sponsor typeOTHER_GOV

Study typeINTERVENTIONAL

Primary completion2023-06

Contact for this trial

Jinjutha Nithiuthai, MD

66806218033 jinjutha.nt@gmail.com

View on ClinicalTrials.gov More Recurrent Febrile Convulsion trials

Who can participate

Age range

6 Months – 60 Months

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.