Stopped: Study abandoned due to drug billing issues
This phase III trial compares the effect of adding tocilizumab to standard of care versus standard of care alone in treating cytokine release syndrome (CRS) in patients with SARS-CoV-2 infection. CRS is a potentially serious disorder caused by the release of an excessive amount of substance that is made by cells of the immune system (cytokines) as a response to viral infection. Tocilizumab is used to decrease the body's immune response. Adding tocilizumab to standard of care may work better in treating CRS in patients with SARS-CoV-2 infection compared to standard of care alone.
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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
7-day length of invasive mechanical ventilation (MV)
Timeframe: Up to 7 days
30-day mortality rate
Timeframe: Up to 30-day after randomization